Gas-Phase IR Spectroscopy of Nucleobases.

نویسنده

  • Mattanjah S de Vries
چکیده

IR spectroscopy of nucleobases in the gas phase reflects simultaneous advances in both experimental and computational techniques. Important properties, such as excited state dynamics, depend in subtle ways on structure variations, which can be followed by their infrared signatures. Isomer specific spectroscopy is a particularly powerful tool for studying the effects of nucleobase tautomeric form and base pair hydrogen-bonding patterns.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pair Formation of Free Nucleobases and Mononucleosides in the Gas Phase

The formation of neutral bimolecular clusters of unsubstituted nucleobases and mononucleosides in the gas phase has been studied by IR laser desorption of the neutral molecules into a supersonic beam expansion. The complementary nucleobase pairs adenine-thymine and cytosine-guanine of DNA have been found to be formed in preference to non complementary base pairs. Association constants for the f...

متن کامل

Interaction of Pyrimidine Nucleobases with Silicon Carbide Nanotube: Effect of Functionalization on Stability and Solvation

This study is about Complexes of Li doped silicon carbide nanotube with Thymine and Cytosine ingas phase and aqueous solutions. Li doped silicon carbide nanotube and its pyrimidine nucleobasecompounds were first modeled by Quantum mechanical calculations in gas phase and in water.Calculated binding energies indicated the stronger ability of thymine to functionalize silicon carbidenanotube than ...

متن کامل

Waveguide-enhanced 2D-IR spectroscopy in the gas phase.

A method for obtaining high-quality 2D-IR spectra of gas-phase samples is presented. Time-resolved IR absorption spectroscopy techniques, such as 2D-IR spectroscopy, often require that beams are focused into the sample. This limits the exploitable overlapped path length through samples to a few millimeters. To circumvent this limitation, 2D-IR experiments have been performed within a hollow wav...

متن کامل

Infrared multiple photon dissociation action spectroscopy of proton-bound dimers of cytosine and modified cytosines: effects of modifications on gas-phase conformations.

The gas-phase structures of proton-bound dimers of cytosine and modified cytosines and their d6-analogues generated by electrospray ionization are probed via infrared multiple photon dissociation (IRMPD) action spectroscopy and theoretical electronic structure calculations. The modified cytosines examined include the 5-methyl-, 5-fluoro-, and 5-bromo-substituted species. IRMPD action spectra of...

متن کامل

Pairing of the nucleobases guanine and cytosine in the gas phase studied by IR–UV double-resonance spectroscopy and ab initio calculations

We present R2PI, IR–UV and UV–UV double resonance measurements of the guanine–cytosine (G–C) dimer formed in a supersonic jet. We show that there is only one isomer of G–C in the investigated wavelength range from 33200 to 34100 cm . We assigned the observed G–C isomer to a specific structure, based on comparisons of the IR spectra of the G and C monomers with the G–C dimer in the range of the ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Topics in current chemistry

دوره 364  شماره 

صفحات  -

تاریخ انتشار 2015